RASGRP3 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS70921
Background:
Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000
Alternative Name:
GRP3,
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: RASGRP3 polyclonal antibody detects endogenous levels of RASGRP3 protein.
Immunogen:
Recombinant protein of human RASGRP3.
MW: ~ 78 kDa
Swis Prot.: Q8IV61
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000
Alternative Name:
GRP3,
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: RASGRP3 polyclonal antibody detects endogenous levels of RASGRP3 protein.
Immunogen:
Recombinant protein of human RASGRP3.
MW: ~ 78 kDa
Swis Prot.: Q8IV61
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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