LC3B (clone 9H5), anti-human
€470.00
In stock
SKU
AC-AP63758
Background:
Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.
Other Names:
MAP1LC3B
Antigen Type: Recombinant Protein
Antigen Type: MAP1LC3B (HGNC:13352)
Gene ID: 81631
Primary Accession: Q9GZQ8
Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.
Other Names:
MAP1LC3B
Antigen Type: Recombinant Protein
Antigen Type: MAP1LC3B (HGNC:13352)
Gene ID: 81631
Primary Accession: Q9GZQ8
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