RB1 Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP8575b
Background:
RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. This protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1.
Other Names:
Retinoblastoma-associated protein, p105-Rb, pRb, Rb, pp110, RB1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8575b was selected from the C-term region of human RB1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: RB1
Gene ID: 5925
Primary Accession: P06400
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. This protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1.
Other Names:
Retinoblastoma-associated protein, p105-Rb, pRb, Rb, pp110, RB1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8575b was selected from the C-term region of human RB1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: RB1
Gene ID: 5925
Primary Accession: P06400
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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