RB1 Antibody (Center S249) Blocking Peptide
€363.00
In stock
SKU
AC-BP16868c
Background:
The protein encoded by this gene is a negative regulatorof the cell cycle and was the first tumor suppressor gene found.The encoded protein also stabilizes constitutive heterochromatin tomaintain the overall chromatin structure. The active,hypophosphorylated form of the protein binds transcription factorE2F1. Defects in this gene are a cause of childhood cancerretinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
Other Names:
Retinoblastoma-associated protein, p105-Rb, pRb, Rb, pp110, RB1
Gene Name: RB1
Gene ID: 5925
Primary Accession: P06400
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene is a negative regulatorof the cell cycle and was the first tumor suppressor gene found.The encoded protein also stabilizes constitutive heterochromatin tomaintain the overall chromatin structure. The active,hypophosphorylated form of the protein binds transcription factorE2F1. Defects in this gene are a cause of childhood cancerretinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
Other Names:
Retinoblastoma-associated protein, p105-Rb, pRb, Rb, pp110, RB1
Gene Name: RB1
Gene ID: 5925
Primary Accession: P06400
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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