RBBP4 antibody (clone 2D7), anti-human
€435.00
In stock
SKU
AC-AT3586a
Catalog Number: AC-AT3586a
Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, IHC, IF, E
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Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, IHC, IF, E
Request Information AC-AT3586a">Request Information
Background:
This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene.
Other Names:
Histone-binding protein RBBP4, Chromatin assembly factor 1 subunit C, CAF-1 subunit C, Chromatin assembly factor I p48 subunit, CAF-I 48 kDa subunit, CAF-I p48, Nucleosome-remodeling factor subunit RBAP48, Retinoblastoma-binding protein 4, RBBP-4, Retinoblastoma-binding protein p48, RBBP4, RBAP48
Antigen Type:
Recombinant Protein
Gene Name: RBBP4
Gene ID: 5928
NCBI Accession: NP_001128727.1;NP_001128728.1;NP_005601.1
Primary Accession: Q09028
Other Accession: BC053904
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene.
Other Names:
Histone-binding protein RBBP4, Chromatin assembly factor 1 subunit C, CAF-1 subunit C, Chromatin assembly factor I p48 subunit, CAF-I 48 kDa subunit, CAF-I p48, Nucleosome-remodeling factor subunit RBAP48, Retinoblastoma-binding protein 4, RBBP-4, Retinoblastoma-binding protein p48, RBBP4, RBAP48
Antigen Type:
Recombinant Protein
Gene Name: RBBP4
Gene ID: 5928
NCBI Accession: NP_001128727.1;NP_001128728.1;NP_005601.1
Primary Accession: Q09028
Other Accession: BC053904
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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