RBP3 Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP17803c
Background:
Interphotoreceptor retinol-binding protein is a largeglycoprotein known to bind retinoids and found primarily in theinterphotoreceptor matrix of the retina between the retinal pigmentepithelium and the photoreceptor cells. It is thought to transportretinoids between the retinal pigment epithelium and thephotoreceptors, a critical role in the visual process.The humanIRBP gene is approximately 9.5 kbp in length and consists of fourexons separated by three introns. The introns are 1.6-1.9 kbp long.The gene is transcribed by photoreceptor and retinoblastoma cellsinto an approximately 4.3-kilobase mRNA that is translated andprocessed into a glycosylated protein of 135,000 Da. The amino acidsequence of human IRBP can be divided into four contiguous homologydomains with 33-38% identity, suggesting a series of geneduplication events. In the gene, the boundaries of these domainsare not defined by exon-intron junctions, as might have beenexpected. The first three homology domains and part of the fourthare all encoded by the first large exon, which is 3,180 base pairslong. The remainder of the fourth domain is encoded in the lastthree exons, which are 191, 143, and approximately 740 base pairslong, respectively.
Other Names:
Retinol-binding protein 3, Interphotoreceptor retinoid-binding protein, IRBP, Interstitial retinol-binding protein, RBP3
Gene Name: RBP3
Gene ID: 5949
Primary Accession: P10745
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Interphotoreceptor retinol-binding protein is a largeglycoprotein known to bind retinoids and found primarily in theinterphotoreceptor matrix of the retina between the retinal pigmentepithelium and the photoreceptor cells. It is thought to transportretinoids between the retinal pigment epithelium and thephotoreceptors, a critical role in the visual process.The humanIRBP gene is approximately 9.5 kbp in length and consists of fourexons separated by three introns. The introns are 1.6-1.9 kbp long.The gene is transcribed by photoreceptor and retinoblastoma cellsinto an approximately 4.3-kilobase mRNA that is translated andprocessed into a glycosylated protein of 135,000 Da. The amino acidsequence of human IRBP can be divided into four contiguous homologydomains with 33-38% identity, suggesting a series of geneduplication events. In the gene, the boundaries of these domainsare not defined by exon-intron junctions, as might have beenexpected. The first three homology domains and part of the fourthare all encoded by the first large exon, which is 3,180 base pairslong. The remainder of the fourth domain is encoded in the lastthree exons, which are 191, 143, and approximately 740 base pairslong, respectively.
Other Names:
Retinol-binding protein 3, Interphotoreceptor retinoid-binding protein, IRBP, Interstitial retinol-binding protein, RBP3
Gene Name: RBP3
Gene ID: 5949
Primary Accession: P10745
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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