Recombinant human Aldo-keto reductase 7A2/AKR7A2 protein
€0.00
In stock
SKU
ATGP0478
Description
Aldo-keto reductases, such as AKR7A2, are involved in the detoxification of aldehydes and ketones. This protein can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the nonbinding AFB1 dialcohol. It may be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen. Also, it has been proposed previously to catalyze the NADPH-dependent reduction of succinic semialdehyde (SSA) to gamma-Hydroxybutyrate in human brain. Recombinant AKR7A2 protein was expressed in E. coli and purified by using conventional chromatography techniques.Alternative Names
Aldo-keto reductase family 7 member A2, Aflatoxin B1 aldehyde reductase member 2, AFB1 aldehyde reductase 1 (AFB1-AR 1), Aldoketoreductase 7, Succinic semialdehyde reductase (SSA reductase), AFAR, AFAR1, AKR7Concentration
0.5mg/ml (determined by Bradford assay)Concentration
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Aldo-keto reductases, such as AKR7A2, are involved in the detoxification of aldehydes and ketones. This protein can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the nonbinding AFB1 dialcohol. It may be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen. Also, it has been proposed previously to catalyze the NADPH-dependent reduction of succinic semialdehyde (SSA) to gamma-Hydroxybutyrate in human brain. Recombinant AKR7A2 protein was expressed in E. coli and purified by using conventional chromatography techniques.Alternative Names
Aldo-keto reductase family 7 member A2, Aflatoxin B1 aldehyde reductase member 2, AFB1 aldehyde reductase 1 (AFB1-AR 1), Aldoketoreductase 7, Succinic semialdehyde reductase (SSA reductase), AFAR, AFAR1, AKR7Concentration
0.5mg/ml (determined by Bradford assay)Concentration
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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