Recombinant human beta -Galactosidase-1/GLB1 protein
€0.00
In stock
SKU
ATGP3290
Description
GLB1, also known as beta-galactosidase, is a lysosomal B-galactosidase that hydrolyzes the terminal B-galactose form ganglioside and keratin sulfate. It plays functional roles in the formation of extracellular elastic fibers (elastogenesis) and in the development of connective tissue. It seems to be identical to the elastin-binding protein (EBP), a major component of the non-integrin cell surface receptor expressed on fibroblasts, smooth muscle cells, chondroblasts, leukocytes, and certain cancer cell types. In elastin producing cells, it associates with tropoelastin intracellularly and functions as a recycling molecular chaperone which facilitates the secretions of tropoelastin and its assembly into elastic fibers. Recombinant human GLB1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.Alternative Names
GLB1, EBP, ELNR1, MPS4BConcentration
0.25mg/ml (determined by absorbance at 280nm)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
GLB1, also known as beta-galactosidase, is a lysosomal B-galactosidase that hydrolyzes the terminal B-galactose form ganglioside and keratin sulfate. It plays functional roles in the formation of extracellular elastic fibers (elastogenesis) and in the development of connective tissue. It seems to be identical to the elastin-binding protein (EBP), a major component of the non-integrin cell surface receptor expressed on fibroblasts, smooth muscle cells, chondroblasts, leukocytes, and certain cancer cell types. In elastin producing cells, it associates with tropoelastin intracellularly and functions as a recycling molecular chaperone which facilitates the secretions of tropoelastin and its assembly into elastic fibers. Recombinant human GLB1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.Alternative Names
GLB1, EBP, ELNR1, MPS4BConcentration
0.25mg/ml (determined by absorbance at 280nm)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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