Recombinant human BMP-14/GDF-5 protein
€0.00
In stock
SKU
ATGP0334
Description
Growth differentiation factor 5 (GDF-5) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This protein plays a role in chondrogenesis and chondrocyte metabolism, tendon and ligament tissue formation, and bone repair. It also increases the survival of neurones that respond to a neurotransmitter called dopamine, and is a potential therapeutic molecule associated with Parkinson's disease. GDF-5, fused to His-tag at N-terminus, was expressed as insoluble protein aggregate in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.Alternative Names
Growth differentiation factor 5, Bone morphogenetic protein 14 (BMP-14), Cartilage-derived morphogenetic protein 1 (CDMP-1), Lipopolysaccharide-associated protein 4 (LAP-4; LPS-associated protein 4), Radotermin, BMP14, CDMP1, LAP4, OS5, SYNS2Concentration
0.5mg/ml (determined by Bradford assay)Concentration
Liquid in. 10mM Sodium Citrate buffer (pH 3.5) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Growth differentiation factor 5 (GDF-5) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This protein plays a role in chondrogenesis and chondrocyte metabolism, tendon and ligament tissue formation, and bone repair. It also increases the survival of neurones that respond to a neurotransmitter called dopamine, and is a potential therapeutic molecule associated with Parkinson's disease. GDF-5, fused to His-tag at N-terminus, was expressed as insoluble protein aggregate in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.Alternative Names
Growth differentiation factor 5, Bone morphogenetic protein 14 (BMP-14), Cartilage-derived morphogenetic protein 1 (CDMP-1), Lipopolysaccharide-associated protein 4 (LAP-4; LPS-associated protein 4), Radotermin, BMP14, CDMP1, LAP4, OS5, SYNS2Concentration
0.5mg/ml (determined by Bradford assay)Concentration
Liquid in. 10mM Sodium Citrate buffer (pH 3.5) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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