Recombinant human CCL2/MCP-1 protein
€0.00
In stock
SKU
ATGP4067
Description
CCL2(Chemokine ligand 2), as known as MCP-1(monocyte chemotactic protein-1), is a small cytokine belonging to the CC chemokine family. This protein recruits monocytes, memory T cells, and dendritic cells to sites of tissue injury and infection. It binds to chemokine receptors CCR2 and CCR4. It also induces enzyme and cytokine release by monocytes, NK cells and lymphocytes, and histamine release by basophils, primarily due to interaction with CCR2 receptors on these cells. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. Recombinant human CCL2/JE/MCP-1, fused to His-tag at C-terminus, was expressed in HEK293 and purified by using conventional chromatography techniques.Alternative Names
SMC-CF, Small inducible cytokine subfamily A member 2, Small inducible cytokine A2, SCYA2, Monocyte secretory protein JE, Monocyte chemotactic protein 1 homologous to mouse Sig-je, Monocyte chemotactic and activating factor, MGC9434, MCP-1, MCP1, MCAF, HC11, GDCF-2, C-C motif chemokine ligand 2Concentration
0.25mg/ml (determined by Absorbance at 280nm)Concentration
Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
CCL2(Chemokine ligand 2), as known as MCP-1(monocyte chemotactic protein-1), is a small cytokine belonging to the CC chemokine family. This protein recruits monocytes, memory T cells, and dendritic cells to sites of tissue injury and infection. It binds to chemokine receptors CCR2 and CCR4. It also induces enzyme and cytokine release by monocytes, NK cells and lymphocytes, and histamine release by basophils, primarily due to interaction with CCR2 receptors on these cells. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. Recombinant human CCL2/JE/MCP-1, fused to His-tag at C-terminus, was expressed in HEK293 and purified by using conventional chromatography techniques.Alternative Names
SMC-CF, Small inducible cytokine subfamily A member 2, Small inducible cytokine A2, SCYA2, Monocyte secretory protein JE, Monocyte chemotactic protein 1 homologous to mouse Sig-je, Monocyte chemotactic and activating factor, MGC9434, MCP-1, MCP1, MCAF, HC11, GDCF-2, C-C motif chemokine ligand 2Concentration
0.25mg/ml (determined by Absorbance at 280nm)Concentration
Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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