Recombinant human CD16b/FCGR3B protein
€0.00
In stock
SKU
ATGP3673
Description
FCGR3B, also known as low affinity immunoglobulin gamma Fc region receptor III-B isoform 2, is a member of Ig super family. It encodes a glycosylphosphatidylinositol (GPI) -anchored protein that is expressed constitutively by neutrophils and after gamma-interferon stimulation by eosinophils. This protein binds to complex or aggregated IgG and monomeric IgG. Unlike III-A, it cannot mediate antibody-dependent cytotoxicity and phagocytosis. It can be a trap of immune complexes in peripheral blood circulation that does not activate neutrophils. Recombinant human FCGR3B, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.Alternative Names
Low affinity immunoglobulin gamma Fc region receptor III-B isoform 2, IgG Fc receptor III-1, IGFR3, FCRIIIb, FCRIII, FCR-10, FCGR3B, FCGR3, FcgammaRIIIb, Fc-gamma RIII-beta, FCG3, Fc gamma receptor IIIb, Fc fragment of IgG receptor IIIb, CD16-I, CD16b, CD16Concentration
0.25mg/ml (determined by absorbance at 280nm)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
FCGR3B, also known as low affinity immunoglobulin gamma Fc region receptor III-B isoform 2, is a member of Ig super family. It encodes a glycosylphosphatidylinositol (GPI) -anchored protein that is expressed constitutively by neutrophils and after gamma-interferon stimulation by eosinophils. This protein binds to complex or aggregated IgG and monomeric IgG. Unlike III-A, it cannot mediate antibody-dependent cytotoxicity and phagocytosis. It can be a trap of immune complexes in peripheral blood circulation that does not activate neutrophils. Recombinant human FCGR3B, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.Alternative Names
Low affinity immunoglobulin gamma Fc region receptor III-B isoform 2, IgG Fc receptor III-1, IGFR3, FCRIIIb, FCRIII, FCR-10, FCGR3B, FCGR3, FcgammaRIIIb, Fc-gamma RIII-beta, FCG3, Fc gamma receptor IIIb, Fc fragment of IgG receptor IIIb, CD16-I, CD16b, CD16Concentration
0.25mg/ml (determined by absorbance at 280nm)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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