Recombinant human DNAJC19 protein
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In stock
SKU
ATGP0911
Description
DNAJC19 is a single-pass membrane protein that contains a J domain and is localized to the inner membrane of the mitochondrion. Expressed ubiquitously, DNAJC19 functions as a component of the mitochondrial DNAJC19 complex, which is responsible for the ATP-dependent translocation of select proteins from the inner mitochondrial membrane to the mitochondrial matrix. Defects in DNAJC19 are the cause of 3-methylglutaconic aciduria type 5 (MGA5), also known as dilated cardiomyopathy with ataxia (DCMA). Recombinant human DNAJC19 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.Alternative Names
Mitochondrial import inner membrane translocase subunit TIM14, Pam18, TIM14, TIMM14Concentration
1mg/ml (determined by Bradford assay)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
DNAJC19 is a single-pass membrane protein that contains a J domain and is localized to the inner membrane of the mitochondrion. Expressed ubiquitously, DNAJC19 functions as a component of the mitochondrial DNAJC19 complex, which is responsible for the ATP-dependent translocation of select proteins from the inner mitochondrial membrane to the mitochondrial matrix. Defects in DNAJC19 are the cause of 3-methylglutaconic aciduria type 5 (MGA5), also known as dilated cardiomyopathy with ataxia (DCMA). Recombinant human DNAJC19 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.Alternative Names
Mitochondrial import inner membrane translocase subunit TIM14, Pam18, TIM14, TIMM14Concentration
1mg/ml (determined by Bradford assay)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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