Recombinant human DTD1 protein
€0.00
In stock
SKU
ATGP1831
Description
DTD1 hydrolyzes D-tyrosyl-tRNA (Tyr) into D-tyrosine and free tRNA (Tyr). It could be a defense mechanism against a harmful effect of D-tyrosine. DTD1 may be a risk factor for aspirin-intolerant asthma (AIA) by catalyzing the hydrolysis of D-tryptophan and interacting with the tyrosyl-tRNA synthetase (tyrRS) enzyme, which promotes a pro-inflammatory phenotype. This protein is localize to the DuE (DNA unwinding element ) s of active replication origins. Recombinant human DTD1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.Alternative Names
D-tyrosyl-tRNA deacylase 1, bA379J5.3, bA555E18.1, C20orf88, DuEB, HARS2, pqn-68Concentration
0.5mg/ml (determined by Bradford assay)Concentration
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTTStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
DTD1 hydrolyzes D-tyrosyl-tRNA (Tyr) into D-tyrosine and free tRNA (Tyr). It could be a defense mechanism against a harmful effect of D-tyrosine. DTD1 may be a risk factor for aspirin-intolerant asthma (AIA) by catalyzing the hydrolysis of D-tryptophan and interacting with the tyrosyl-tRNA synthetase (tyrRS) enzyme, which promotes a pro-inflammatory phenotype. This protein is localize to the DuE (DNA unwinding element ) s of active replication origins. Recombinant human DTD1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.Alternative Names
D-tyrosyl-tRNA deacylase 1, bA379J5.3, bA555E18.1, C20orf88, DuEB, HARS2, pqn-68Concentration
0.5mg/ml (determined by Bradford assay)Concentration
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTTStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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