Recombinant human EXOSC8 protein
€0.00
In stock
SKU
ATGP2629
Description
EXOSC8, also known as exosome component 8 and transcription factor 4, is a part of the exosome complex. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing Au-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. EXOSC8 binds to ARE-containing RNAs. Recombinant human EXOSC8 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.Alternative Names
Exosome complex component RRP43, bA421P11.3, CIP3, EAP2, OIP2, p9, RP11- 421P11.3, RRP43, Rrp43pConcentration
0.25mg/ml (determined by Bradford assay)Concentration
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 50% glycerol 0.2M NaCl,1mM DTTStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
EXOSC8, also known as exosome component 8 and transcription factor 4, is a part of the exosome complex. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing Au-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. EXOSC8 binds to ARE-containing RNAs. Recombinant human EXOSC8 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.Alternative Names
Exosome complex component RRP43, bA421P11.3, CIP3, EAP2, OIP2, p9, RP11- 421P11.3, RRP43, Rrp43pConcentration
0.25mg/ml (determined by Bradford assay)Concentration
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 50% glycerol 0.2M NaCl,1mM DTTStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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