Recombinant Human Fc epsilon RI alpha protein
€0.00
In stock
SKU
ATGP4124
Description
Fc epsilon RI alpha, also known as FCER1A, is an IgE‑binding protein of the multichain immune recognition family. Fc epsilon receptor is a tetrameric complex of one alpha, one beta and two gamma subunits on mast cells and basophils. This protein represents the alpha subunit, only the alpha subunit is glycosylated. The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. A perturbation occurs that brings about the release of histamine and proteases from the granules in the cytoplasm of the mast cell and leads to the synthesis of prostaglandins and leukotrienes—potent effectors of the hypersensitivity response. Recombinant human Fc epsilon RI alpha/FCER1A, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.Alternative Names
High affinity immunoglobulin epsilon receptor subunit alpha isoform1, FCERIA, FCERA, Fc epsilon receptor Ia, Fc-epsilon RI-alpha, Fc epsilon RI alpha chain, FcERI, IgE Fc receptor subunit alpha, FCER1A, FCE1AConcentration
1mg/ml (determined by Absorbance at 280nm)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Fc epsilon RI alpha, also known as FCER1A, is an IgE‑binding protein of the multichain immune recognition family. Fc epsilon receptor is a tetrameric complex of one alpha, one beta and two gamma subunits on mast cells and basophils. This protein represents the alpha subunit, only the alpha subunit is glycosylated. The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. A perturbation occurs that brings about the release of histamine and proteases from the granules in the cytoplasm of the mast cell and leads to the synthesis of prostaglandins and leukotrienes—potent effectors of the hypersensitivity response. Recombinant human Fc epsilon RI alpha/FCER1A, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.Alternative Names
High affinity immunoglobulin epsilon receptor subunit alpha isoform1, FCERIA, FCERA, Fc epsilon receptor Ia, Fc-epsilon RI-alpha, Fc epsilon RI alpha chain, FcERI, IgE Fc receptor subunit alpha, FCER1A, FCE1AConcentration
1mg/ml (determined by Absorbance at 280nm)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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