Recombinant human GM3 Synthase/ST3GAL5 protein
€0.00
In stock
SKU
ATGP2418
Description
Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in this gene has been associated with Amish infantile epilepsy syndrome. Transcript variants encoding different isoforms have been found for this gene. Recombinant human ST3GAL5 protein, fused to His-tag at N-terminus, was expressed in E. coli.Alternative Names
"ST3 beta-galactoside alpha-2,3-sialyltransferase 5", "Lactosylceramide alpha-2,3-sialyltransferase", "CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase", GM3 synthase, Ganglioside GM3 synthase, ST3Gal V, Sialyltransferase 9, SIAT9Concentration
1mg/ml (determined by Bradford assay)Concentration
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M ureaStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in this gene has been associated with Amish infantile epilepsy syndrome. Transcript variants encoding different isoforms have been found for this gene. Recombinant human ST3GAL5 protein, fused to His-tag at N-terminus, was expressed in E. coli.Alternative Names
"ST3 beta-galactoside alpha-2,3-sialyltransferase 5", "Lactosylceramide alpha-2,3-sialyltransferase", "CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase", GM3 synthase, Ganglioside GM3 synthase, ST3Gal V, Sialyltransferase 9, SIAT9Concentration
1mg/ml (determined by Bradford assay)Concentration
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M ureaStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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