Recombinant human GULP1/CED-6 protein
€0.00
In stock
SKU
ATGP2009
Description
PTB domain-containing engulfment adapter protein 1, also known as GuLP1, is an evolutionarily conserved adaptor protein required for efficient engulfment of apoptotic cells by phagocytes. GuLP1 also helps modulate cellular glycosphingolipid and cholesterol transport. It also may play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increased cytoplasmic levels of GuLP1 are associated with increases in cellular levels of GTP-bound ARF6. Recombinant human GuLP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.Alternative Names
PTB domain-containing engulfment adapter protein 1, CED-6, GuLPConcentration
0.5mg/ml (determined by Bradford assay)Concentration
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 50% glycerol, 2mM DTTStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
PTB domain-containing engulfment adapter protein 1, also known as GuLP1, is an evolutionarily conserved adaptor protein required for efficient engulfment of apoptotic cells by phagocytes. GuLP1 also helps modulate cellular glycosphingolipid and cholesterol transport. It also may play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increased cytoplasmic levels of GuLP1 are associated with increases in cellular levels of GTP-bound ARF6. Recombinant human GuLP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.Alternative Names
PTB domain-containing engulfment adapter protein 1, CED-6, GuLPConcentration
0.5mg/ml (determined by Bradford assay)Concentration
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 50% glycerol, 2mM DTTStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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