Recombinant human HMGA1 protein
€0.00
In stock
SKU
ATGP1140
Description
High mobility group protein HMG-I/HMG-Y, also known as HMGA1, is a member of the non-histone chromosomal high mobility group protein (HMG) family. HMGA1 consists of a highly conserved AT-hook DNA-binding domain that mediates binding to AT-rich sequences in the minor groove of chromosomal DNA. It functions as architectural chromatin-binding transcription factor altering the conformation of DNA by modulating nuclear protein-DNA complexes. It is involved in many cellular processes including growth regulation, viral induction of beta-IFN gene and regulation of inducible gene transcription. Recombinant human HMGA1 protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.Alternative Names
High mobility group protein HMG-I/HMG-Y, HMG-R, HMGA1A, HMGIYConcentration
0.25mg/ml (determined by BCA assay)Concentration
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 50% glycerol, 0.2M NaClStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
High mobility group protein HMG-I/HMG-Y, also known as HMGA1, is a member of the non-histone chromosomal high mobility group protein (HMG) family. HMGA1 consists of a highly conserved AT-hook DNA-binding domain that mediates binding to AT-rich sequences in the minor groove of chromosomal DNA. It functions as architectural chromatin-binding transcription factor altering the conformation of DNA by modulating nuclear protein-DNA complexes. It is involved in many cellular processes including growth regulation, viral induction of beta-IFN gene and regulation of inducible gene transcription. Recombinant human HMGA1 protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.Alternative Names
High mobility group protein HMG-I/HMG-Y, HMG-R, HMGA1A, HMGIYConcentration
0.25mg/ml (determined by BCA assay)Concentration
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 50% glycerol, 0.2M NaClStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
| Is Featured? | No |
|---|
Write Your Own Review