Recombinant human Hyaluronidase 1/HYAL1 protein
€0.00
In stock
SKU
ATGP3941
Description
HYAL1, also known as Hyaluronidase-1, is a member of the endolytic glycoside hydrolase family. Human hyaluronidases (HYALs) are a group of five endoβNacetylhexosaminidases that include HYAL1, HYAL2, HYAL3, HYAL4, and SPAM1 (PH20). HYAL1 preferentially degrades hyaluronic acid present in the extracellular matrix of somatic tissues. This protein is active at an acidic pH and is the major hyaluronidase in plasma. Defects in HYAL1 are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. It is implicated in several types of cancers, likely due to the angiogenic effects of HYAL1-cleaved hyaluronan fragments. Recombinant human HYAL1, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.Alternative Names
Hyaluronidase-1, Hyal-1,Hyaluronoglucosaminidase-1, Lung carcinoma protein 1, LuCa-1, HYAL1, Hyaluronidase 1, Hyaluronoglucosaminidase 1, Hyaluronoglucosaminidase1, LUCA 1,MPS9, NAT6, Plasma hyaluronidase, Tumor suppressor LUCA 1Concentration
0.25mg/ml (determined by Absorbance at 280nm)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol.Storage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
HYAL1, also known as Hyaluronidase-1, is a member of the endolytic glycoside hydrolase family. Human hyaluronidases (HYALs) are a group of five endoβNacetylhexosaminidases that include HYAL1, HYAL2, HYAL3, HYAL4, and SPAM1 (PH20). HYAL1 preferentially degrades hyaluronic acid present in the extracellular matrix of somatic tissues. This protein is active at an acidic pH and is the major hyaluronidase in plasma. Defects in HYAL1 are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. It is implicated in several types of cancers, likely due to the angiogenic effects of HYAL1-cleaved hyaluronan fragments. Recombinant human HYAL1, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.Alternative Names
Hyaluronidase-1, Hyal-1,Hyaluronoglucosaminidase-1, Lung carcinoma protein 1, LuCa-1, HYAL1, Hyaluronidase 1, Hyaluronoglucosaminidase 1, Hyaluronoglucosaminidase1, LUCA 1,MPS9, NAT6, Plasma hyaluronidase, Tumor suppressor LUCA 1Concentration
0.25mg/ml (determined by Absorbance at 280nm)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol.Storage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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