Recombinant human I-TAC/CXCL11 protein
€0.00
In stock
SKU
ATGP1296
Description
Chemokine (C-X-C motif) ligand 11 (CXCL11) is a small cytokine belonging to the CXC chemokine family that is also called Interferon-inducible T-cell alpha chemoattractant (I-TAC) and Interferon-gamma-inducible protein 9 (IP-9). CXCL11 is strongly induced by IFN-gamma and IFN-beta, and weakly induced by IFN-alpha. It is chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. It is highly expressed in peripheral blood leukocytes, pancreas and liver, with moderate levels in thymus, spleen and lung and low expression levels were in small intestine, placenta and prostate. Recombinant human CXCL11 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.Alternative Names
C-X-C motif chemokine ligand 11, C-X-C motif chemokine 11, Beta-R1, H174, Interferon gamma-inducible protein 9, IP-9, Interferon-inducible T-cell alpha chemoattractant, I-TAC, Small-inducible cytokine B11, SCYB11, SCYB9B, b-R1, IP-9Concentration
1mg/ml (determined by Bradford assay)Concentration
Liquid in. 10mM Sodium Citrate buffer (pH 3.5) containing 2mM DTT, 20% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Chemokine (C-X-C motif) ligand 11 (CXCL11) is a small cytokine belonging to the CXC chemokine family that is also called Interferon-inducible T-cell alpha chemoattractant (I-TAC) and Interferon-gamma-inducible protein 9 (IP-9). CXCL11 is strongly induced by IFN-gamma and IFN-beta, and weakly induced by IFN-alpha. It is chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. It is highly expressed in peripheral blood leukocytes, pancreas and liver, with moderate levels in thymus, spleen and lung and low expression levels were in small intestine, placenta and prostate. Recombinant human CXCL11 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.Alternative Names
C-X-C motif chemokine ligand 11, C-X-C motif chemokine 11, Beta-R1, H174, Interferon gamma-inducible protein 9, IP-9, Interferon-inducible T-cell alpha chemoattractant, I-TAC, Small-inducible cytokine B11, SCYB11, SCYB9B, b-R1, IP-9Concentration
1mg/ml (determined by Bradford assay)Concentration
Liquid in. 10mM Sodium Citrate buffer (pH 3.5) containing 2mM DTT, 20% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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