Recombinant human IL-15R alpha/IL15RA protein
€0.00
In stock
SKU
ATGP3672
Description
IL15RA, also known as interleukin-15 receptor subunit alpha isoform 1, is a high-affinity receptor for interleukin-15. It associates as a heterotrimer with the IL-2 receptor beta and gamma subunits to initiate signal transduction. This protein can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. IL15/IL15R alpha complexes can transmit reverse signaling that promotes cellular adhesion, tyrosine phosphorylation of intracellular proteins, and cytokine secretion by the IL 15/IL15R alpha expressing cells. Recombinant human IL15RA protein, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.Alternative Names
Interleukin-15 receptor subunit alpha isoform 1, IL15RA, CD215, IL-15 receptor subunit alphaConcentration
0.5mg/ml (determined by absorbance at 280nm)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
IL15RA, also known as interleukin-15 receptor subunit alpha isoform 1, is a high-affinity receptor for interleukin-15. It associates as a heterotrimer with the IL-2 receptor beta and gamma subunits to initiate signal transduction. This protein can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. IL15/IL15R alpha complexes can transmit reverse signaling that promotes cellular adhesion, tyrosine phosphorylation of intracellular proteins, and cytokine secretion by the IL 15/IL15R alpha expressing cells. Recombinant human IL15RA protein, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.Alternative Names
Interleukin-15 receptor subunit alpha isoform 1, IL15RA, CD215, IL-15 receptor subunit alphaConcentration
0.5mg/ml (determined by absorbance at 280nm)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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