Recombinant human IPP-1/PPP1R1A protein
€0.00
In stock
SKU
IPP0801
Description
Protein phosphatase inhibitor-1 (IPP-1) plays an important role in the regulation of glycogen metabolism through inhibition of type-1 protein serine/threonine phosphatase (PP1) activity, and it has been implicated in the regulation of cell growth. IPP-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. In the presence of calcium, PPI-1 is inactivated by calcineurin (or PP2B). Recombinant human IPP-1, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.Alternative Names
Protein phosphatase inhibitor-1, Protein phosphatase inhibitor, Protein phosphatase inhibitor-1 Protein phosphatase inhibitor 1, I 1, I1, Inhibitor 1, IPP 1, IPP1, PPP1R1A, Protein phosphatase 1 regulatory (inhibitor) subunit 1A, Protein phosphatase 1 regulatory subunit 1A.Concentration
1mg/ml (determined by Bradford assay)Concentration
Liquid in. 50mM Tris-HCl buffer (pH 8.0) containing 0.1mM PMSF, 1mM EDTA, 1mM DTT, 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Protein phosphatase inhibitor-1 (IPP-1) plays an important role in the regulation of glycogen metabolism through inhibition of type-1 protein serine/threonine phosphatase (PP1) activity, and it has been implicated in the regulation of cell growth. IPP-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. In the presence of calcium, PPI-1 is inactivated by calcineurin (or PP2B). Recombinant human IPP-1, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.Alternative Names
Protein phosphatase inhibitor-1, Protein phosphatase inhibitor, Protein phosphatase inhibitor-1 Protein phosphatase inhibitor 1, I 1, I1, Inhibitor 1, IPP 1, IPP1, PPP1R1A, Protein phosphatase 1 regulatory (inhibitor) subunit 1A, Protein phosphatase 1 regulatory subunit 1A.Concentration
1mg/ml (determined by Bradford assay)Concentration
Liquid in. 50mM Tris-HCl buffer (pH 8.0) containing 0.1mM PMSF, 1mM EDTA, 1mM DTT, 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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