Recombinant human JNK3/MAPK10 protein
€0.00
In stock
SKU
ATGP3837
Description
MAPK10, also known as mitogen-activated protein kinase 10, is a member of the MAP kinase family. This group of protein kinases includes at least 10 members that interact selectively with ATF2, Jun and Elk-i transcription factors. It acts as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Also, expression of multiple JNK isoforms provides a mechanism for the generation of tissue-specific responses to the activation of the JNK signal transduction pathway. Recombinant human MAPK10, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.Alternative Names
Mitogen-activated protein kinase 10, MAPK10, JNK3, JNK3A, p493F12, p54bSAPK, PRKM10, SAPK1bConcentration
0.25mg/ml (determined by Bradford assay)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 30% glycerol, 1mM DTT, 0.1mM PMSFStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
MAPK10, also known as mitogen-activated protein kinase 10, is a member of the MAP kinase family. This group of protein kinases includes at least 10 members that interact selectively with ATF2, Jun and Elk-i transcription factors. It acts as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Also, expression of multiple JNK isoforms provides a mechanism for the generation of tissue-specific responses to the activation of the JNK signal transduction pathway. Recombinant human MAPK10, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.Alternative Names
Mitogen-activated protein kinase 10, MAPK10, JNK3, JNK3A, p493F12, p54bSAPK, PRKM10, SAPK1bConcentration
0.25mg/ml (determined by Bradford assay)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 30% glycerol, 1mM DTT, 0.1mM PMSFStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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