Recombinant human Kallikrein 10/KLK10 protein
€0.00
In stock
SKU
ATGP3834
Description
KLK10, also known as kallikrein-10, is belong to the subgroup of serine proteases encompassing fifteen homologous members. This protein is widely expressed in normal human organs, for example breast, prostate, thyroid, testis, ovary, and gastrointestinal tract. Interestingly, it is highly expressed in the islets of Langerhans in human pancreas. Also, it is detectable in many biological fluids, including milk, seminal plasma, amniotic fluid, serum, and cerebrospinal fluid. In spite of its unknown physiological functions, the implications of KLK10 in various diseases have been explored. Early studies have shown that this expression is dramatically down-regulated in breast and testicular germ-cell tumors. It is secreted and may play a role in suppression of tumorigenesis in breast. Recombinant human KLK10, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.Alternative Names
PRSSL1, Protease serine-like 1, Normal epithelial cell-specific 1, NES1, KLK10, Kallikrein-10, Kallikrein related peptidase 10Concentration
0.5mg/ml (determined by absorbance at 280nm)Concentration
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 1mM DTT, 30% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
KLK10, also known as kallikrein-10, is belong to the subgroup of serine proteases encompassing fifteen homologous members. This protein is widely expressed in normal human organs, for example breast, prostate, thyroid, testis, ovary, and gastrointestinal tract. Interestingly, it is highly expressed in the islets of Langerhans in human pancreas. Also, it is detectable in many biological fluids, including milk, seminal plasma, amniotic fluid, serum, and cerebrospinal fluid. In spite of its unknown physiological functions, the implications of KLK10 in various diseases have been explored. Early studies have shown that this expression is dramatically down-regulated in breast and testicular germ-cell tumors. It is secreted and may play a role in suppression of tumorigenesis in breast. Recombinant human KLK10, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.Alternative Names
PRSSL1, Protease serine-like 1, Normal epithelial cell-specific 1, NES1, KLK10, Kallikrein-10, Kallikrein related peptidase 10Concentration
0.5mg/ml (determined by absorbance at 280nm)Concentration
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 1mM DTT, 30% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
| Is Featured? | No |
|---|
Write Your Own Review