Recombinant human Kallikrein 7/KLK7 protein
€0.00
In stock
SKU
ATGP1737
Description
KLK7 is a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikreins are biomarkers for cancer. The protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. KLK7 may play a role in cancer invasion and metastasis, and increased expression of this protein is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Recombinant human KLK7 protein, fused to His-tag at N-terminus, was expressed in E. coli.Alternative Names
Stratum corneum chymotryptic enzyme, Serine protease 6, SCCE, PRSS6, KLK7, Kallikrein-7 isoform 2, Kallikrein-7, Kallikrein related peptidase 7, HK7Concentration
1mg/ml (determined by Bradford assay)Concentration
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 2M uREA, 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
KLK7 is a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikreins are biomarkers for cancer. The protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. KLK7 may play a role in cancer invasion and metastasis, and increased expression of this protein is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Recombinant human KLK7 protein, fused to His-tag at N-terminus, was expressed in E. coli.Alternative Names
Stratum corneum chymotryptic enzyme, Serine protease 6, SCCE, PRSS6, KLK7, Kallikrein-7 isoform 2, Kallikrein-7, Kallikrein related peptidase 7, HK7Concentration
1mg/ml (determined by Bradford assay)Concentration
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 2M uREA, 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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