Recombinant human LILRB2/CD85d/ILT4 protein
€0.00
In stock
SKU
ATGP4042
Description
LILRB2, also known as CD85d, LIR-2, and MIR10, is a member of the leukocyte immunoglobulin-like receptor (LIR) family. It is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. Among them it competes with CD8 alpha for MHC I binding but does not compete with KIR2DL1. And it binds to classical MHC I proteins as well as the non-classical HLA-G1 and HLA-F molecules. This protein is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Recombinant human LILRB2, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.Alternative Names
Leukocyte Immunoglobulin-like Receptor, CD85D, CD85d, CD85 antigen-like family member D, CD85d antigen, ILT-4, ILT4, ILT4CD85d, Ig-like transcript 4, Immunoglobulin-like transcript 4, LILRB2, LIR2, LIR-2, LIR2CD85D, Leukocyte immunoglobulin-like receptor 2, MIR10, MIR-10, MIR10LILRA6, Monocyte/macrophage immunoglobulin-like receptor 10, leukocyte immunoglobulin-like receptor subfamily B member 2, leukocyte immunoglobulin-like receptor subfamily B member 2 soluble isoform 1Concentration
0.5mg/ml (determined by absorbance at 280nm)Concentration
Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 20% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
LILRB2, also known as CD85d, LIR-2, and MIR10, is a member of the leukocyte immunoglobulin-like receptor (LIR) family. It is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. Among them it competes with CD8 alpha for MHC I binding but does not compete with KIR2DL1. And it binds to classical MHC I proteins as well as the non-classical HLA-G1 and HLA-F molecules. This protein is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Recombinant human LILRB2, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.Alternative Names
Leukocyte Immunoglobulin-like Receptor, CD85D, CD85d, CD85 antigen-like family member D, CD85d antigen, ILT-4, ILT4, ILT4CD85d, Ig-like transcript 4, Immunoglobulin-like transcript 4, LILRB2, LIR2, LIR-2, LIR2CD85D, Leukocyte immunoglobulin-like receptor 2, MIR10, MIR-10, MIR10LILRA6, Monocyte/macrophage immunoglobulin-like receptor 10, leukocyte immunoglobulin-like receptor subfamily B member 2, leukocyte immunoglobulin-like receptor subfamily B member 2 soluble isoform 1Concentration
0.5mg/ml (determined by absorbance at 280nm)Concentration
Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 20% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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