Recombinant human NKp80/KLRF1 protein
€0.00
In stock
SKU
ATGP4063
Description
NKp80/KLRF1, also known as killer cell lectin-like receptor subfamily F member 1, is a member of the C-type lectin family. Multiple splicing variants produce four isoforms for NKp80/KLRF1 and isoform 1 is the standard protein. It is expressed on NK cells and a subset of T lymphocytes whereas it is not expressed on B lymphocytes, monocytes and granulocytes. It stimulates NK cell cytotoxicity and induces calcium influx after triggering by appropriate antibodies. It works through interaction with its ligand, AICL (activation-induced C-type lectin), which is selectively expressed on myeloid cells. NKp80-AICL interaction regulates the immune responses at sites of inflammation by stimulating the release of proinflammatory cytokines. Recombinant human NKp80/KLRF1, fused to hIgG-His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.Alternative Names
Killer cell lectin-like receptor F1, Killer cell lectin-like receptor subfamily F member 1,Killer cell lectin-like receptor subfamily F member 1 isoform 1, Lectin-like receptor F1, Activating coreceptor NKp80, NKp80, KLRF1, C-type lectin domain family 5 member C, CLEC5C, ML, CLEC5CMGC119908, MGC119907, MGC119909Concentration
0.25mg/ml (determined by Absorbance at 280nm)Concentration
Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
NKp80/KLRF1, also known as killer cell lectin-like receptor subfamily F member 1, is a member of the C-type lectin family. Multiple splicing variants produce four isoforms for NKp80/KLRF1 and isoform 1 is the standard protein. It is expressed on NK cells and a subset of T lymphocytes whereas it is not expressed on B lymphocytes, monocytes and granulocytes. It stimulates NK cell cytotoxicity and induces calcium influx after triggering by appropriate antibodies. It works through interaction with its ligand, AICL (activation-induced C-type lectin), which is selectively expressed on myeloid cells. NKp80-AICL interaction regulates the immune responses at sites of inflammation by stimulating the release of proinflammatory cytokines. Recombinant human NKp80/KLRF1, fused to hIgG-His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.Alternative Names
Killer cell lectin-like receptor F1, Killer cell lectin-like receptor subfamily F member 1,Killer cell lectin-like receptor subfamily F member 1 isoform 1, Lectin-like receptor F1, Activating coreceptor NKp80, NKp80, KLRF1, C-type lectin domain family 5 member C, CLEC5C, ML, CLEC5CMGC119908, MGC119907, MGC119909Concentration
0.25mg/ml (determined by Absorbance at 280nm)Concentration
Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
| Is Featured? | No |
|---|
Write Your Own Review