Recombinant human NUDT3/DIPP1 protein
€0.00
In stock
SKU
ATGP0922
Description
NuDT3, also known as DIPP, DIPP1 (diphosphoinositol polyphosphate phosphohydrolase 1), is a 172 amino acid cytoplasmic protein belonging to the nudix hydrolase family and DIPP subfamily. NuDT3 acts as a negative regulator of the ERK 1/2 pathway and hydrolyzes 5-phosphoribose 1-diphosphate. NuDT3 exists as a monomer and binds magnesium as a cofactor. Also NuDT3 is widely expressed but found at highest levels in liver, pancreas, brain and heart. Recombinant human NuDT3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.Alternative Names
Nudix hydrolase 3, Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1, Diphosphoinositol polyphosphate phosphohydrolase 1Concentration
0.5mg/ml (determined by Bradford assay)Concentration
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 5mM DTT, 20% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
NuDT3, also known as DIPP, DIPP1 (diphosphoinositol polyphosphate phosphohydrolase 1), is a 172 amino acid cytoplasmic protein belonging to the nudix hydrolase family and DIPP subfamily. NuDT3 acts as a negative regulator of the ERK 1/2 pathway and hydrolyzes 5-phosphoribose 1-diphosphate. NuDT3 exists as a monomer and binds magnesium as a cofactor. Also NuDT3 is widely expressed but found at highest levels in liver, pancreas, brain and heart. Recombinant human NuDT3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.Alternative Names
Nudix hydrolase 3, Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1, Diphosphoinositol polyphosphate phosphohydrolase 1Concentration
0.5mg/ml (determined by Bradford assay)Concentration
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 5mM DTT, 20% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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