Recombinant human PAIP2 protein
€0.00
In stock
SKU
ATGP0416
Description
PAIP2, also known as Poly (A) -binding protein-interacting protein 2, acts as a repressor in the regulation of translation initiation of poly (A) -containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. It displaces the interaction of PABPC1 with poly (A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly (A) RNP structure organization. Recombinant PAIP2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.Alternative Names
Poly(A)-binding protein-interacting protein 2, PAIP2A, PABP- interacting protein 2, HSPC218, Poly(A)-binding protein-interacting protein 2 poly(A) binding protein interacting protein 2.Concentration
1mg/ml (determined by Bradford assay)Concentration
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
PAIP2, also known as Poly (A) -binding protein-interacting protein 2, acts as a repressor in the regulation of translation initiation of poly (A) -containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. It displaces the interaction of PABPC1 with poly (A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly (A) RNP structure organization. Recombinant PAIP2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.Alternative Names
Poly(A)-binding protein-interacting protein 2, PAIP2A, PABP- interacting protein 2, HSPC218, Poly(A)-binding protein-interacting protein 2 poly(A) binding protein interacting protein 2.Concentration
1mg/ml (determined by Bradford assay)Concentration
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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