Recombinant human Semaphorin 3C(R551A/R552A/R611A/R612A) protein
€0.00
In stock
SKU
ATGP4059
Description
Semaphorin 3C , also known as SemaE, is a member of the semaphorin family 3 that are grouped into eight major classes based on structure and phylogenetic tree analyses. It is expressed in all somitic motor neurons, in lung buds, and in cardiac neural crest cells during development. The functions of Semaphorin 3C are mediated primarily through binding to the Plexin-D1 and Neuropilin 1 or Neuropilin 2 coreceptor complex. Semaphorins are usually cues to deflect axons from inappropriate regions, especially important in the neural system development. Also, Semaphorin 3C activates integrins in certain cells, so in addition to its repulsive activities, it sometimes acts as a chemoattractant. Class 3 have an important function after traumatic central nervous system injuries, such as spinal cord injury. It regulate neuronal and non-neuronal cells associated with the traumatic injury due to their presence in the scar tissue. Recombinant human Semaphorin 3C, fused to hIgG-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.Alternative Names
Semaphorin 3C ,Semaphorin-3C, Semaphorin-3C isoform2, SEMA3C, Semaphorin-E, SEMAE, Sema E, SemE, SEME, Semaphorin EConcentration
1mg/ml (determined by Absorbance at 280nm)Concentration
Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Semaphorin 3C , also known as SemaE, is a member of the semaphorin family 3 that are grouped into eight major classes based on structure and phylogenetic tree analyses. It is expressed in all somitic motor neurons, in lung buds, and in cardiac neural crest cells during development. The functions of Semaphorin 3C are mediated primarily through binding to the Plexin-D1 and Neuropilin 1 or Neuropilin 2 coreceptor complex. Semaphorins are usually cues to deflect axons from inappropriate regions, especially important in the neural system development. Also, Semaphorin 3C activates integrins in certain cells, so in addition to its repulsive activities, it sometimes acts as a chemoattractant. Class 3 have an important function after traumatic central nervous system injuries, such as spinal cord injury. It regulate neuronal and non-neuronal cells associated with the traumatic injury due to their presence in the scar tissue. Recombinant human Semaphorin 3C, fused to hIgG-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.Alternative Names
Semaphorin 3C ,Semaphorin-3C, Semaphorin-3C isoform2, SEMA3C, Semaphorin-E, SEMAE, Sema E, SemE, SEME, Semaphorin EConcentration
1mg/ml (determined by Absorbance at 280nm)Concentration
Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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