Recombinant human SH2D1A protein

Recombinant human SH2D1A protein

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In stock
SKU
ATGP0783
Catalog NumberATGP0783
Applications:
SDS-PAGE
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Description
SH2D1A is an inhibitor of the signaling lymphocyte activation molecule (SLAM) self-association. This protein is expressed at a high level in thymus and lung, with a lower level of expression in spleen and liver. Defects in SH2D1A are a cause of X-linked lymphoproliferative disease (XLPD) also known as Duncan disease. XLPD is characterized by a rare congenital immunodeficiency following Epstein-Barr virus (EBV) infection. Recombinant human SH2D1A protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.Alternative Names
SH2 domain-containing protein 1A, DSHP, EBVS, IMD5, LYP, MTCP1, SAP, XLP, XLPDConcentration
1mg/ml (determined by Bradford assay)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4)Storage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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