Recombinant human SIRP gamma/CD172g protein
€0.00
In stock
SKU
ATGP4030
Description
SIRPG, also known as signal-regulatory protein gamma isoform 1, is a member of a closely related family of three cell surface receptors implicated in modulating immune/inflammatory responses. It is the only SIRP known to be expressed on T cells, CD56 bright NK cells and activated NK cells. Expression of SIRPG on T cells suggests a role as an accessory protein interacting with CD47‑expressing antigen presenting cells. Engagement of CD47 by SIRPG was shown to induce apoptosis on T-cell and monocyte cell lines. Recombinant human SIRPG, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.Alternative Names
Signal-regulatory protein gamma isoform 1, SIRPG, bA77C3.1, CD172g, SIRP-B2, SIRPB2, SIRPgammaConcentration
0.5mg/ml (determined by absorbance at 280nm)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
SIRPG, also known as signal-regulatory protein gamma isoform 1, is a member of a closely related family of three cell surface receptors implicated in modulating immune/inflammatory responses. It is the only SIRP known to be expressed on T cells, CD56 bright NK cells and activated NK cells. Expression of SIRPG on T cells suggests a role as an accessory protein interacting with CD47‑expressing antigen presenting cells. Engagement of CD47 by SIRPG was shown to induce apoptosis on T-cell and monocyte cell lines. Recombinant human SIRPG, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.Alternative Names
Signal-regulatory protein gamma isoform 1, SIRPG, bA77C3.1, CD172g, SIRP-B2, SIRPB2, SIRPgammaConcentration
0.5mg/ml (determined by absorbance at 280nm)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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