Recombinant human SRSF1 protein
€0.00
In stock
SKU
ATGP3558
Description
SRSF1, also known as Serine/arginine-rich splicing factor 1, is a member of the arginine/serine-rich splicing factor protein family, and functions in both constitutive and alternative pre-mRNA splicing. This protein binds to pre-mRNA transcripts and components of the spliceosome, and can either activate or repress splicing depending on the location of the pre-mRNA binding site. The protein's ability to activate splicing is regulated by phosphorylation and interactions with other splicing factor associated proteins. In addition to being involved in the splicing process, it also mediates post-splicing activities, such as mRNA nuclear export and translation. Recombinant human SRSF1 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.Alternative Names
Serine/arginine-rich splicing factor 1, SRSF1, ASF, SF2, SF2p33, SFRS1, SRp30aConcentration
0.25mg/ml (determined by Bradford Assay)Concentration
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 100mM KCl, 1mM DTT, 0.2mM EDTA, 40% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
SRSF1, also known as Serine/arginine-rich splicing factor 1, is a member of the arginine/serine-rich splicing factor protein family, and functions in both constitutive and alternative pre-mRNA splicing. This protein binds to pre-mRNA transcripts and components of the spliceosome, and can either activate or repress splicing depending on the location of the pre-mRNA binding site. The protein's ability to activate splicing is regulated by phosphorylation and interactions with other splicing factor associated proteins. In addition to being involved in the splicing process, it also mediates post-splicing activities, such as mRNA nuclear export and translation. Recombinant human SRSF1 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.Alternative Names
Serine/arginine-rich splicing factor 1, SRSF1, ASF, SF2, SF2p33, SFRS1, SRp30aConcentration
0.25mg/ml (determined by Bradford Assay)Concentration
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 100mM KCl, 1mM DTT, 0.2mM EDTA, 40% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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