Recombinant human TCL1A protein
€0.00
In stock
SKU
ATGP0391
Description
TCL1A, also known as T-cell leukemia/lymphoma 1A, is a protein with a suggested role in intracellular regulation of T cell signaling. TCL1A binds to the pleckstrin homology domain of Akt (protein kinase B) family proteins, which facilitates Akt dimerization and activity. By increasing Akt activity TCL1A may enhance the serine/threonine phosphorylation of major Akt signaling substrates, such as Ikk complex, mTOR, BAD, p70S6 kinase, FOXO transcription factors, and GSK3b. These substrates regulate cellular differentiation, growth, survival, and metabolism. Recombinant TCL1A protein was expressed in E. coli and purified by using conventional chromatography techniquesAlternative Names
T-cell leukemia/lymphoma 1A, TCL1, TCL-1, protein p14TCL1, Oncogene TCL1, T-cell leukemia/lymphoma 1A anti TCL1A, P14 TCL1, P14 TCL1 protein, T cell leukemia 1, T cell lymphoma 1, T cell lymphoma 1A, TCL 1 protein, TCL1 oncogene, TCL1 PEN, TCL1A, TCL1A.Concentration
1mg/ml (determined by Bradford assay)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4)Storage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
TCL1A, also known as T-cell leukemia/lymphoma 1A, is a protein with a suggested role in intracellular regulation of T cell signaling. TCL1A binds to the pleckstrin homology domain of Akt (protein kinase B) family proteins, which facilitates Akt dimerization and activity. By increasing Akt activity TCL1A may enhance the serine/threonine phosphorylation of major Akt signaling substrates, such as Ikk complex, mTOR, BAD, p70S6 kinase, FOXO transcription factors, and GSK3b. These substrates regulate cellular differentiation, growth, survival, and metabolism. Recombinant TCL1A protein was expressed in E. coli and purified by using conventional chromatography techniquesAlternative Names
T-cell leukemia/lymphoma 1A, TCL1, TCL-1, protein p14TCL1, Oncogene TCL1, T-cell leukemia/lymphoma 1A anti TCL1A, P14 TCL1, P14 TCL1 protein, T cell leukemia 1, T cell lymphoma 1, T cell lymphoma 1A, TCL 1 protein, TCL1 oncogene, TCL1 PEN, TCL1A, TCL1A.Concentration
1mg/ml (determined by Bradford assay)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4)Storage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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