Recombinant human TIMP-4 protein
€0.00
In stock
SKU
ATGP3407
Description
TIMP4, as known as metalloproteinase inhibitor 4, is a family of secreted protein that regulates the activation and proteolytic activity of the zinc enzymes known as matrix metalloproteinases. There are four known members of the family, TIMP1, 2, 3 and 4. TIMP4 is produced by a wide range of tissues, particularly brain, heart, ovary and skeletal muscle. Limited studies have shown that this protein has a tumor suppressive effect against Wilm s tumor, exhibits negative correlation with glioma malignancy and is found in breast carcinoma cells. Recombinant human TIMP4, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.Alternative Names
Metalloproteinase inhibitor 4, TIMP4, TIMP-4, Metalloproteinase inhibitor 4, TIMP 4, TIMP metallopeptidase inhibitor 4, TIMP-4, Timp4, TIMP4_HUMAN, Tissue inhibitor of metalloproteinase 4, Tissue inhibitor of metalloproteinases 4Concentration
0.25mg/ml (determined by absorbance at 280nm)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
TIMP4, as known as metalloproteinase inhibitor 4, is a family of secreted protein that regulates the activation and proteolytic activity of the zinc enzymes known as matrix metalloproteinases. There are four known members of the family, TIMP1, 2, 3 and 4. TIMP4 is produced by a wide range of tissues, particularly brain, heart, ovary and skeletal muscle. Limited studies have shown that this protein has a tumor suppressive effect against Wilm s tumor, exhibits negative correlation with glioma malignancy and is found in breast carcinoma cells. Recombinant human TIMP4, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.Alternative Names
Metalloproteinase inhibitor 4, TIMP4, TIMP-4, Metalloproteinase inhibitor 4, TIMP 4, TIMP metallopeptidase inhibitor 4, TIMP-4, Timp4, TIMP4_HUMAN, Tissue inhibitor of metalloproteinase 4, Tissue inhibitor of metalloproteinases 4Concentration
0.25mg/ml (determined by absorbance at 280nm)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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