Recombinant human Troponin C2/TNNC2 protein
€0.00
In stock
SKU
ATGP0332
Description
Troponin C, skeletal muscle, also known as TNNC2, is the central regulatory protein of striated muscle contraction, and modulates the Ca2+-activation characteristics of muscle fibers. Troponin has 3 subunits, Troponin I (Tn-1), Troponin T (Tn-T) and Troponin C (Tn-C). Tn-I subunit inhibits actomyosin ATPase and Tn-T subunit binds tropomyosin and Tn-C, while Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. Mutations in all components of this complex have been associated with skeletal muscle disease. Recombinant human Troponin C was expressed in E. coli and purified by using conventional chromatography.Alternative Names
Troponin C2, Troponin C1 slow, Troponin C type 2 (fast), Troponin C type 1 (slow), Troponin C skeletal muscle, Troponin C, TNNC2, TNNC, Slow skeletal and cardiac muscles, Skeletal troponin C, Skeletal muscle TNNC1, Fast skeletal type, Fast skeletal muscle troponin C, FAP85, CFAP85, Cardiac troponin CConcentration
1mg/ml (determined by Bradford assay)Concentration
Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 1mM DTT, 100mM NaCl, 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Troponin C, skeletal muscle, also known as TNNC2, is the central regulatory protein of striated muscle contraction, and modulates the Ca2+-activation characteristics of muscle fibers. Troponin has 3 subunits, Troponin I (Tn-1), Troponin T (Tn-T) and Troponin C (Tn-C). Tn-I subunit inhibits actomyosin ATPase and Tn-T subunit binds tropomyosin and Tn-C, while Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. Mutations in all components of this complex have been associated with skeletal muscle disease. Recombinant human Troponin C was expressed in E. coli and purified by using conventional chromatography.Alternative Names
Troponin C2, Troponin C1 slow, Troponin C type 2 (fast), Troponin C type 1 (slow), Troponin C skeletal muscle, Troponin C, TNNC2, TNNC, Slow skeletal and cardiac muscles, Skeletal troponin C, Skeletal muscle TNNC1, Fast skeletal type, Fast skeletal muscle troponin C, FAP85, CFAP85, Cardiac troponin CConcentration
1mg/ml (determined by Bradford assay)Concentration
Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 1mM DTT, 100mM NaCl, 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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