Recombinant human TYRP1 protein
€0.00
In stock
SKU
ATGP3435
Description
TYRP1, also known as 5, 6-dihydroxyindole-2-carboxylic acid oxidase, is a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. It is a melanocyte-specific gene product involved in eumelanin synthesis. It is involved in the oxidation of 5, 6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5, 6-quinone-2-carboxylic acid. It is regulated by the microphthalmia-associated transcription factor (MITF). Recombinant human TYRP1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.Alternative Names
5, 6-dihydroxyindole-2-carboxylic acid oxidase, TYRP1, b-PROTEIN, CAS2, CATB, GP75, OCA3, TRP, TRP1, TYRPConcentration
0.25mg/ml (determined by absorbance at 280nm)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
TYRP1, also known as 5, 6-dihydroxyindole-2-carboxylic acid oxidase, is a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. It is a melanocyte-specific gene product involved in eumelanin synthesis. It is involved in the oxidation of 5, 6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5, 6-quinone-2-carboxylic acid. It is regulated by the microphthalmia-associated transcription factor (MITF). Recombinant human TYRP1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.Alternative Names
5, 6-dihydroxyindole-2-carboxylic acid oxidase, TYRP1, b-PROTEIN, CAS2, CATB, GP75, OCA3, TRP, TRP1, TYRPConcentration
0.25mg/ml (determined by absorbance at 280nm)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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