Recombinant human ULBP-2 protein
€0.00
In stock
SKU
ATGP3491
Description
ULBP2, also known as NKG2D ligand 2, is a member of a family of cell-surface proteins that function as ligands for human NKG2D. Carithromycin induces ULBP2 expression and reduces the amount of sULBP2, by possibly inhibiting the activity of the potent ULBP2-shedding enzyme ADAM17. Because these changes in ULBP2 and sULBP2 levels could activate NKT cells, this finding might indicate a novel mechanism by which clarithromycin improves the clearance of P. aeruginosa in chronic respiratory diseases. It is a useful serum biomarker for pancreatic cancer detection. Recombinant human ULBP2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.Alternative Names
UL16 binding protein 2, ALCAN-alpha, NKG2D ligand 2, N2DL-2, NKG2DL2, Retinoic acid early transcript 1H, RAET1H, N2DL2Concentration
0.5mg/ml (determined by absorbance at 280nm)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
ULBP2, also known as NKG2D ligand 2, is a member of a family of cell-surface proteins that function as ligands for human NKG2D. Carithromycin induces ULBP2 expression and reduces the amount of sULBP2, by possibly inhibiting the activity of the potent ULBP2-shedding enzyme ADAM17. Because these changes in ULBP2 and sULBP2 levels could activate NKT cells, this finding might indicate a novel mechanism by which clarithromycin improves the clearance of P. aeruginosa in chronic respiratory diseases. It is a useful serum biomarker for pancreatic cancer detection. Recombinant human ULBP2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.Alternative Names
UL16 binding protein 2, ALCAN-alpha, NKG2D ligand 2, N2DL-2, NKG2DL2, Retinoic acid early transcript 1H, RAET1H, N2DL2Concentration
0.5mg/ml (determined by absorbance at 280nm)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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