Recombinant human Visinin-like protein-1/VILIP protein
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In stock
SKU
ATGP0384
Description
Visinin-like protein-1, also known as VILIP-1, belongs to a family of neuronal calcium sensor proteins. VILIP-1 is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Also, it is expressed in pancreatic beta-cells. VILIP-1 elevation enhances insulin secretion in cAMP-associated manner. Down-regulation of VILIP-1 decreased cAMP accumulation but increased insulin gene transcription. Recombinant human Visinin-like protein-1 was expressed in E. coli and purified by using conventional chromatography.Alternative Names
VILIP, VILIP-1, VLP-1, HLP3, VSNL1, Hippocalcin like protein 3, HLP 3, HPCAL 3, HPCAL3, HuVISL1, Neurocalcin alpha, NVL 1, NVL1, VILIP, Visinin.Visinin like 1, Visinin like protein 1.VISL 1.Concentration
1mg/ml (determined by Bradford assay)Concentration
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT,10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Visinin-like protein-1, also known as VILIP-1, belongs to a family of neuronal calcium sensor proteins. VILIP-1 is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Also, it is expressed in pancreatic beta-cells. VILIP-1 elevation enhances insulin secretion in cAMP-associated manner. Down-regulation of VILIP-1 decreased cAMP accumulation but increased insulin gene transcription. Recombinant human Visinin-like protein-1 was expressed in E. coli and purified by using conventional chromatography.Alternative Names
VILIP, VILIP-1, VLP-1, HLP3, VSNL1, Hippocalcin like protein 3, HLP 3, HPCAL 3, HPCAL3, HuVISL1, Neurocalcin alpha, NVL 1, NVL1, VILIP, Visinin.Visinin like 1, Visinin like protein 1.VISL 1.Concentration
1mg/ml (determined by Bradford assay)Concentration
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT,10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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