Recombinant mouse Cathepsin C/DPPI protein
€0.00
In stock
SKU
ATGP4093
Description
Cathepsin C/DPPI, also known as dipeptidyl peptidase I , is a lysosomal exo-cysteine protease belonging to the peptidase C1 protein family, a subgroup of the cysteine cathepsins. It catalyses excision of dipeptides from the N-terminus of protein and peptide substrates, except if the amino group of the N-terminus is blocked. Also, It appears to be a central coordinator for activation of many serine proteases in immune/inflammatory cells. Defects in the Cathepsin C have been shown to be a cause of Papillon-Lefevre disease, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Also, It plays a key role in the activation of several degradative enzymes linked to tissue destruction in inflammatory diseases. Recombinant mouse Cathepsin C, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.Alternative Names
Cathepsin C, AI047818, CatC, DP, DPP1, DPPI, Cathepsin J, Dipeptidyl peptidase isoform 1, Dipeptidyl peptidase 1, Dipeptidyl transferase, CTSCConcentration
0.5mg/ml (determined by Absorbance at 280nm)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Cathepsin C/DPPI, also known as dipeptidyl peptidase I , is a lysosomal exo-cysteine protease belonging to the peptidase C1 protein family, a subgroup of the cysteine cathepsins. It catalyses excision of dipeptides from the N-terminus of protein and peptide substrates, except if the amino group of the N-terminus is blocked. Also, It appears to be a central coordinator for activation of many serine proteases in immune/inflammatory cells. Defects in the Cathepsin C have been shown to be a cause of Papillon-Lefevre disease, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Also, It plays a key role in the activation of several degradative enzymes linked to tissue destruction in inflammatory diseases. Recombinant mouse Cathepsin C, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.Alternative Names
Cathepsin C, AI047818, CatC, DP, DPP1, DPPI, Cathepsin J, Dipeptidyl peptidase isoform 1, Dipeptidyl peptidase 1, Dipeptidyl transferase, CTSCConcentration
0.5mg/ml (determined by Absorbance at 280nm)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
| Is Featured? | No |
|---|
Write Your Own Review