Recombinant mouse DKK1 protein
€0.00
In stock
SKU
ATGP4071
Description
Dkk-1, also known as Dickkopf-related protein 1, is a member of the Dkk protein family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Because of its antagonistic effects on the Wnt signaling pathway, it is believed that Dkk-1 is a common marker for neuronal death in neurodegenerative diseases like Alzheimer’s. Elevated level of Dkk-1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. Recombinant mouse Dkk-1, fused to His-tag at C-terminus, was expressed in HEK293 and purified by using conventional chromatography techniques.Alternative Names
mDkk-1, Dkk-1, Dickkopf-related protein 1, Dickkopf-1, Dickkopf WNT signaling pathway inhibitor 1Concentration
0.25mg/ml (determined by Absorbance at 280nm)Concentration
Liquid in. 50mM MES buffer (pH 6.5) containing 30% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Dkk-1, also known as Dickkopf-related protein 1, is a member of the Dkk protein family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Because of its antagonistic effects on the Wnt signaling pathway, it is believed that Dkk-1 is a common marker for neuronal death in neurodegenerative diseases like Alzheimer’s. Elevated level of Dkk-1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. Recombinant mouse Dkk-1, fused to His-tag at C-terminus, was expressed in HEK293 and purified by using conventional chromatography techniques.Alternative Names
mDkk-1, Dkk-1, Dickkopf-related protein 1, Dickkopf-1, Dickkopf WNT signaling pathway inhibitor 1Concentration
0.25mg/ml (determined by Absorbance at 280nm)Concentration
Liquid in. 50mM MES buffer (pH 6.5) containing 30% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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