Recombinant mouse LIFR alpha/LIFR Protein
€0.00
In stock
SKU
ATGP3958
Description
LIFR alpha, also known as CD118, is a member of the Interleukin-6 receptor family. Members of this family mediate the biological effects of Cardiotrophin-1, CLC, CNTF, IL-6, IL-11, IL-27, and Oncostatin M. The leukemia inhibitory factor is a polyfunctional cytokine that affects the differentiation, survival, and proliferation of a wide variety of cells in the adult and the embryo. LIFR alpha has also been identified as a breast cancer metastasis suppressor that functions through the HIPPO-YAP pathway. LIFR alpha is down regulated in a number of breast carcinomas and may serve a prognostic tool. Recombinant mouse LIFR alpha, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.Alternative Names
Leukemia inhibitory factor receptor, LIF receptor, LIF-R, LIF receptor subunit alpha, D-factor, CD118Concentration
0.25mg/ml (determined by Absorbance at 280nm)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
LIFR alpha, also known as CD118, is a member of the Interleukin-6 receptor family. Members of this family mediate the biological effects of Cardiotrophin-1, CLC, CNTF, IL-6, IL-11, IL-27, and Oncostatin M. The leukemia inhibitory factor is a polyfunctional cytokine that affects the differentiation, survival, and proliferation of a wide variety of cells in the adult and the embryo. LIFR alpha has also been identified as a breast cancer metastasis suppressor that functions through the HIPPO-YAP pathway. LIFR alpha is down regulated in a number of breast carcinomas and may serve a prognostic tool. Recombinant mouse LIFR alpha, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.Alternative Names
Leukemia inhibitory factor receptor, LIF receptor, LIF-R, LIF receptor subunit alpha, D-factor, CD118Concentration
0.25mg/ml (determined by Absorbance at 280nm)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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