Recombinant mouse Mer protein
€0.00
In stock
SKU
ATGP3906
Description
Mer, also known as Tyrosine-protein kinase Mer, is one of the receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm. It regulates many physiological processes including cell survival, migration, differentiation, and phagocytosis of apoptotic cells. This protein plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment. Mutations in this protein have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). Recombinant mouse Mer, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.Alternative Names
Mertk, Proto-oncogene c-Mer, Receptor tyrosine kinase MerTK, Eyk, Mer, nmf12, Nyk,Tyrosine-protein kinase MerConcentration
0.5mg/ml (determined by absorbance at 280nm)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Mer, also known as Tyrosine-protein kinase Mer, is one of the receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm. It regulates many physiological processes including cell survival, migration, differentiation, and phagocytosis of apoptotic cells. This protein plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment. Mutations in this protein have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). Recombinant mouse Mer, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.Alternative Names
Mertk, Proto-oncogene c-Mer, Receptor tyrosine kinase MerTK, Eyk, Mer, nmf12, Nyk,Tyrosine-protein kinase MerConcentration
0.5mg/ml (determined by absorbance at 280nm)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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