Recombinant mouse VE-Cadherin/CDH5 protein
€0.00
In stock
SKU
ATGP3209
Description
CDH5, also known as cadherin-5, is a classical cadherin from the cadherin superfamily and the gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. Recombinant mouse CDH5, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.Alternative Names
Cdh5, 7B4, AA408225, Cd144, VE-Cad, Vec, VEcad, VECD, Vascular endothelial cadherinConcentration
0.5mg/ml (determined by absorbance at 280nm)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
CDH5, also known as cadherin-5, is a classical cadherin from the cadherin superfamily and the gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. Recombinant mouse CDH5, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.Alternative Names
Cdh5, 7B4, AA408225, Cd144, VE-Cad, Vec, VEcad, VECD, Vascular endothelial cadherinConcentration
0.5mg/ml (determined by absorbance at 280nm)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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