Recombinant Rat DYRK1A protein
€0.00
In stock
SKU
ATGP2720
Description
DYRK1A is a member of the dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidin6e repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. Recombinant rat DYRK1A protein, fused to His-tag at N-terminus, was expressed in E. coli.Alternative Names
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, Dual Specificity Yak1-related kinase, Dyrk; PSK47Concentration
1mg/ml (determined by Bradford assay)Concentration
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M ureaStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
DYRK1A is a member of the dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidin6e repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. Recombinant rat DYRK1A protein, fused to His-tag at N-terminus, was expressed in E. coli.Alternative Names
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, Dual Specificity Yak1-related kinase, Dyrk; PSK47Concentration
1mg/ml (determined by Bradford assay)Concentration
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M ureaStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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