Recombinant Rat UNC5H2/UNC5B protein
€0.00
In stock
SKU
ATGP3950
Description
UNC5B/UNC5B, also known as Netrin receptor UNC5B, is one of four related receptors that comprise the UNC5 family and serve as receptors for the axon guidance molecule Netrin-1. Outside of the nervous system, UNC5B facilitates Netrin-1-mediated inhibition of capillary branching and leukocyte migration, as well as Netrin-1-mediated promotion of osteoclast differentiation. Also this protein activates DAPK1 which mediates apoptosis. It is believed to play a role in tumorgenesis. Additionally, It is thought to play a critical role in the development of atherosclerosis and the survival of renal tubular epithelial cells during acute kidney injury. Recombinant Rat UNC5B/UNC5B, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.Alternative Names
unc-5 netrin receptor B, Unc5h2, unc-5 homolog 2, Protein unc-5 homolog B, netrin receptor UNC5B precursor, netrin receptor UNC5B, protein unc-5 homolog 2, unc5bConcentration
0.25mg/ml (determined by Absorbance at 280nm)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
UNC5B/UNC5B, also known as Netrin receptor UNC5B, is one of four related receptors that comprise the UNC5 family and serve as receptors for the axon guidance molecule Netrin-1. Outside of the nervous system, UNC5B facilitates Netrin-1-mediated inhibition of capillary branching and leukocyte migration, as well as Netrin-1-mediated promotion of osteoclast differentiation. Also this protein activates DAPK1 which mediates apoptosis. It is believed to play a role in tumorgenesis. Additionally, It is thought to play a critical role in the development of atherosclerosis and the survival of renal tubular epithelial cells during acute kidney injury. Recombinant Rat UNC5B/UNC5B, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.Alternative Names
unc-5 netrin receptor B, Unc5h2, unc-5 homolog 2, Protein unc-5 homolog B, netrin receptor UNC5B precursor, netrin receptor UNC5B, protein unc-5 homolog 2, unc5bConcentration
0.25mg/ml (determined by Absorbance at 280nm)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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