RET monoclonal (Ascites), anti-human
€470.00
In stock
SKU
AC-AM1869a
Catalog Number: AC-AM1869a
Size: 100 µl
Isotype: mouse IgMκ
Clone Name: 188CT11.2.3
Applications: IF, IHC-P, WB
Datasheet
Request Information
Size: 100 µl
Isotype: mouse IgMκ
Clone Name: 188CT11.2.3
Applications: IF, IHC-P, WB
Datasheet
Request Information
Background:
This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed.
Other Names:
Proto-oncogene tyrosine-protein kinase receptor Ret, Cadherin family member 12, Proto-oncogene c-Ret, Soluble RET kinase fragment, Extracellular cell-membrane anchored RET cadherin 120 kDa fragment, RET, CDHF12, CDHR16, PTC, RET51
Target/Specificity:
This RET Monoclonal antibody was raised using purified His-tagged recombinant human RET.
Antigen Type: Recombinant Protein
Gene Name: RET {ECO:0000303|PubMed:2660074, ECO:0000312|HGNC:HGNC:9967}
Gene ID: 5979
Primary Accession: P07949
NCBI Accession: NP_065681.1;NP_066124.1
Other Accession: NP_065681.1;NP_066124.1
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed.
Other Names:
Proto-oncogene tyrosine-protein kinase receptor Ret, Cadherin family member 12, Proto-oncogene c-Ret, Soluble RET kinase fragment, Extracellular cell-membrane anchored RET cadherin 120 kDa fragment, RET, CDHF12, CDHR16, PTC, RET51
Target/Specificity:
This RET Monoclonal antibody was raised using purified His-tagged recombinant human RET.
Antigen Type: Recombinant Protein
Gene Name: RET {ECO:0000303|PubMed:2660074, ECO:0000312|HGNC:HGNC:9967}
Gene ID: 5979
Primary Accession: P07949
NCBI Accession: NP_065681.1;NP_066124.1
Other Accession: NP_065681.1;NP_066124.1
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
| Is Featured? | No |
|---|
Write Your Own Review