Ret (phospho Tyr1062) Polyclonal Antibody
€0.00
In stock
SKU
ELK-ES7032
Catalog Number: ELK-ES7032
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-p, ELISA
Information
Request Manual ELK-
Questions? Contact us!
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-p, ELISA
Information
Request Manual ELK-
Questions? Contact us!
Background:
ret proto-oncogene(RET) Homo sapiens This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq, Jul 2008],
Alternative Names:
RET, CDHF12, CDHR16, PTC, RET51, Proto-oncogene tyrosine-protein kinase receptor Ret, Cadherin family member 12, Proto-oncogene c-Ret
Immunogen: The antiserum was produced against synthesized peptide derived from human Ret around the phosphorylation site of Tyr1062. AA range:1041-1090
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 170
GeneID: RET
Storage: -20°C/1 year
NOTE: For Research Use Only
ret proto-oncogene(RET) Homo sapiens This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq, Jul 2008],
Alternative Names:
RET, CDHF12, CDHR16, PTC, RET51, Proto-oncogene tyrosine-protein kinase receptor Ret, Cadherin family member 12, Proto-oncogene c-Ret
Immunogen: The antiserum was produced against synthesized peptide derived from human Ret around the phosphorylation site of Tyr1062. AA range:1041-1090
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 170
GeneID: RET
Storage: -20°C/1 year
NOTE: For Research Use Only
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