hCAP-H polyclonal, anti-human
€470.00
In stock
SKU
AC-AP70289
Background:
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (PubMed:11136719). Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size (PubMed:27737959).
Other Names:
NCAPH; BRRN; BRRN1; CAPH; KIAA0074; Condensin complex subunit 2; Barren homolog protein 1; Chromosome-associated protein H; hCAP-H; Non-SMC condensin I complex subunit H; XCAP-H homolog
Antigen Type: synthetic peptide
Antigen Type: NCAPH {ECO:0000303|PubMed:27737959, ECO:0000312|HGNC:HGNC:1112}
Gene ID: 23397
Primary Accession: Q15003
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (PubMed:11136719). Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size (PubMed:27737959).
Other Names:
NCAPH; BRRN; BRRN1; CAPH; KIAA0074; Condensin complex subunit 2; Barren homolog protein 1; Chromosome-associated protein H; hCAP-H; Non-SMC condensin I complex subunit H; XCAP-H homolog
Antigen Type: synthetic peptide
Antigen Type: NCAPH {ECO:0000303|PubMed:27737959, ECO:0000312|HGNC:HGNC:1112}
Gene ID: 23397
Primary Accession: Q15003
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