RFC4 antibody (clone 1C12), anti-human
€435.00
In stock
SKU
AC-AT3621a
Catalog Number: AC-AT3621a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, E
Request Information AC-AT3621a">Request Information
Background:
The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported.
Other Names:
Replication factor C subunit 4, Activator 1 37 kDa subunit, A1 37 kDa subunit, Activator 1 subunit 4, Replication factor C 37 kDa subunit, RF-C 37 kDa subunit, RFC37, RFC4
Antigen Type:
Recombinant Protein
Gene Name: RFC4
Gene ID: 5984
NCBI Accession: NP_002907.1;NP_853551.1
Primary Accession: P35249
Other Accession: BC017452
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported.
Other Names:
Replication factor C subunit 4, Activator 1 37 kDa subunit, A1 37 kDa subunit, Activator 1 subunit 4, Replication factor C 37 kDa subunit, RF-C 37 kDa subunit, RFC37, RFC4
Antigen Type:
Recombinant Protein
Gene Name: RFC4
Gene ID: 5984
NCBI Accession: NP_002907.1;NP_853551.1
Primary Accession: P35249
Other Accession: BC017452
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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